This postal service was updated on Feb 2, 2017.

If you regularly use the E-utilities API, we accept important news for you: NCBI is at present providing API keys for the Eastward-utilities! After May one, 2018, NCBI will limit your admission to the Due east-utilities unless you have one of these keys. Obtaining an API key is quick, and unproblematic, and will allow you to access NCBI data faster. If y'all don't have an API central, E-utilities volition still work, but y'all may be limited to fewer requests than allowed with an API fundamental.

What is an API key?

An API fundamental is a unique cord that you include in your HTTP requests that identifies you to NCBI servers. Think of the API central as a 'turbocharger' that lets you become more than information, faster, from NCBI.

Why are we doing this?

  • Sustainability. The E-utilities API is a free service open to the public and will continue to be; however, without any limits, a single user making too many requests could slow down the service for others. Limiting usage for non-API primal users will proceed the service faster for everyone.
  • Security. Internet security threats abound, and having key-restricted access better enables us to protect the service from malicious attacks and other forms of abuse.
  • Functioning. API keys give united states of america greater insight into how the community is using the Due east-utilities, thereby assisting us in making them a meliorate service for you.

Who needs to get a key?

For virtually coincidental use, you lot won't need an API cardinal at all – you only need to become ane if you lot look to access East-utilities at a rate of more than than three requests per 2nd from a single computer (IP accost). Even for higher rates of usage, you won't need a cardinal earlier May one, 2018. After May 1, 2018, any calculator (IP accost) that submits more than iii E-utility requests per second will receive an error message. This limit applies to any combination of requests to EInfo, ESearch, ESummary, EFetch, ELink, EPost, ESpell, and EGquery. Just to be clear, this rate applies simply to when we receive the asking, not to how long the request executes. You lot can have more than iii concurrent requests running equally long as y'all don't initiate more than three requests in any ane-second window. Fifty-fifty though you won't need a fundamental before May 1,  keys are already available. You lot can get one now and brainstorm using it correct away.

How do I go a key?

Outset, yous will demand an NCBI business relationship. Registering is piece of cake. If you already take an NCBI account, you're good to go.

To create the central, become to the "Settings" folio of your NCBI business relationship. (Hint: after signing in, only click on your NCBI username in the upper right corner of whatever NCBI folio.)

You'll see a new "API Primal Management" surface area. Click the "Create an API Key" push button, and re-create the resulting key. Utilize the key past adding the parameter api_key to any E-utilities asking.

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Case: Let'due south say that you create a primal and its value is "ABCD123". This would be a simple EInfo request that includes your key:

https://www.ncbi.nlm.nih.gov/entrez/eutils/einfo.fcgi?db=pubmed&api_key=ABCD123

Now that I have a central, are in that location even so access limits?

Yes. Past default, your primal will increment the limit to 10 requests/second for all activeness from that fundamental. If we receive requests at a higher frequency that include the same central, all requests using that key will receive an error bulletin. If you need higher rates of access, please contact us and we can hash out your situation.

Keep in mind that the request limit applies to all requests using a given primal, regardless of the IP address. So if multiple computers are using the same fundamental, then if thesum of their activity causes the asking charge per unit to exceed 10 per 2d, thenall of those computers volition receive errors.

Hither'due south what you demand to call up:

  • Requests without a fundamental will be charge per unit-limited by all activity from their IP address.
  • Requests with a key will exist rate-limited by all action from that fundamental.

Here'south another scenario: let'south say computer A and B both share the aforementioned IP address, only only A is using a key. A posts 7 requests / 2d, while B posts 2 requests / 2d. A will be fine, simply B will receive errors. Why? Since B does not include a primal, B'south requests are limited by the IP address, which also includes A's activeness. So the total for that IP is ix requests / second, which exceeds the limit of three requests / second, resulting in errors for B. A does not receive errors because A'south activity is limited by A's fundamental, which is only producing 7 requests / second, beneath the limit of 10 requests / second.

How many keys tin I get?

We allow only ane API key for each NCBI account. If for any reason yous want to replace an existing key with a new i, you can do that on your NCBI account settings page.

I writer software that accesses the E-utilities, and this software is used by other people. Do those users demand keys?

Yes, but just if your software allows them to postal service more than than three requests/second. For such cases, we recommend that you allow users to enter their ain API primal as a setting in the software.  Please contact us if you take questions or for more information on this approach.

Questions?

Please contact us if yous take whatsoever questions or concerns about these new keys, and stay tuned to this blog and our documentation for updates.